Christopher Ritchlin, MD, MPH

Christopher Ritchlin, MD, MPH

Biography

Christopher Ritchlin, MD, MPH is a Professor of Medicine and Director of the Rheumatology Fellowship Program and the Clinical Immunology Research Center at the University of Rochester Medical Center in Rochester, New York. He attended medical school at Albany Medical College and completed his medical residency and chief residency at Mt Sinai Hospital in New York. He trained as a fellow in rheumatology at the New York University Medical Center and remained as a postdoctoral fellow for 2 years and then spent an additional year in the lab of Dr. Robin Poole in Montreal, Canada. He joined the faculty of the University of Rochester School of Medicine and Dentistry in 1991. In 2009, he earned an MPH degree at the University.

Dr. Ritchlin is engaged in translational research that is centered on mechanisms of bone resorption in psoriatic arthritis and on the role of the lymphatic system in joint flares observed in both rheumatoid and psoriatic arthritis. His laboratory has a number of ongoing projects including circulating osteoclast precursors in inflammatory joint disease and psoriasis, mechanisms of inflammatory osteolysis in psoriatic arthritis, and gene activation profiles in the blood and end organs of patients with immune mediated inflammatory disorders. The lab is also examining the contribution of circulating dendritic cells to inflammation in rheumatoid and psoriatic arthritis. His research is funded by the NIH, National Psoriasis foundation, Amgen, Centocor and UCB. He is also a co-investigator in the IPART and CORRONA registries and he leads an effort to identify arthritis biomarkers in psoriasis patients. He is chair of the Professional Meetings Committee of the American College of Rheumatology and also directs the mentoring of junior investigators in the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA). He has published over 100 manuscripts on topics related to psoriatic arthritis, lymphatic mechanisms of joint flare and bone remodeling.

Publications

  1. Ritchlin CT, Haas-Smith SA, Li P, Hicks DG, Schwarz EM: Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis. J Clin Invest 2003, 111(6):821-831.
  2. Anandarajah AP, Ritchlin CT: The diagnosis and treatment of early psoriatic arthritis. Nat Rev Rheumatol 2009, 5(11):634-641.
  3. Ritchlin C: The quest for a biomarker of circulating osteoclast precursors. Arthritis Res Ther 2009, 11(3):113.
  4. Ritchlin CT, Kavanaugh A, Gladman DD, Mease PJ, Helliwell P, Boehncke WH, de Vlam K, Fiorentino D, Fitzgerald O, Gottlieb AB et al: Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 2009, 68(9):1387-1394.
  5. Chiu YG, Shao T, Feng C, Mensah KA, Thullen M, Schwarz EM, Ritchlin CT: CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis. Arthritis Res Ther 2010, 12(1):R14.
  6. Kwok WE, You Z, Monu J, Seo G, Ritchlin C: High-resolution uniform MR imaging of finger joints using a dedicated RF coil at 3T. J Magn Reson Imaging 2010, 31(1):240-247.

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